Journal of Interventional Cardiology (Jan 2023)

The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial

  • Quan Guo,
  • Liang Peng,
  • Lixin Rao,
  • Cao Ma,
  • Kang Zhao,
  • Zhenzhou Zhao,
  • Haiyu Tang,
  • Muwei Li

DOI
https://doi.org/10.1155/2023/6889836
Journal volume & issue
Vol. 2023

Abstract

Read online

Background. This study explored the efficacy of the “L-sandwich” strategy, which involves the implantation of stents in the main vessel (MV) and shaft of the side branch (SB) with a drug-coated balloon (DCB) applied to the SB ostium, for coronary true bifurcation lesions. Methods and Results. Of 99 patients with true bifurcation lesions, 38 patients underwent the “L-sandwich” strategy (group A), 32 patients underwent a two-stent strategy (group B), and 29 patients underwent a single-stent + DCB strategy (group C). Angiography outcomes (late lumen loss [LLL], minimum lumen diameter [MLD]), and clinical outcomes (major adverse cardiac events [MACEs]) were analyzed. At 6 months, the MLD of the SB ostium in groups A and B were similar (P>0.05) and group A larger than group C (P0.05), and patients in the other groups had no MACEs. Conclusions. The “L-sandwich” strategy was feasible for the treatment of true coronary bifurcation lesions. It is a simpler procedure with similar acute lumen gain than the two-stent strategy, results in a larger SB lumen than the single-stent + DCB strategy, and it can also be used as a remedy for dissection following the single-stent + DCB strategy.