mSystems (Jun 2021)

Genomic and Phenotypic Evolution of Achromobacter xylosoxidans during Chronic Airway Infections of Patients with Cystic Fibrosis

  • S. M. Hossein Khademi,
  • Migle Gabrielaite,
  • Magnus Paulsson,
  • Mattis Knulst,
  • Eleni Touriki,
  • Rasmus L. Marvig,
  • Lisa I. Påhlman

DOI
https://doi.org/10.1128/mSystems.00523-21
Journal volume & issue
Vol. 6, no. 3

Abstract

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A thorough understanding of bacterial pathogen adaptation is essential for the treatment of chronic bacterial infections. One unique challenge in the analysis and interpretation of genomics data is identifying the function impact of mutations accumulated in the bacterial genome during colonization in the human host.