Facile sonochemical-assisted synthesis of orthorhombic phase black phosphorus/rGO hybrids for effective photothermal therapy
Liang Weiyuan,
Wang Dou,
Ren Xiaohui,
Ge Chenchen,
Wang Hanyue,
Li Zhongjun,
Liu Quan,
Qiu Meng,
Du Zhiyong,
Qi Xiang,
Xu Yijun,
Liu Liping,
Bao Shiyun,
Zhang Han
Affiliations
Liang Weiyuan
Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P.R. China
Wang Dou
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Ren Xiaohui
Hunan Key Laboratory of Micro-Nano Energy Materials and Devices, Laboratory for Quantum Engineering and Micro-Nano Energy Technology and School of Physics and Optoelectronic, Xiangtan University, Hunan 411105, P.R. China
Ge Chenchen
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Wang Hanyue
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Li Zhongjun
Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P.R. China
Liu Quan
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Qiu Meng
Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P.R. China
Du Zhiyong
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Qi Xiang
Hunan Key Laboratory of Micro-Nano Energy Materials and Devices, Laboratory for Quantum Engineering and Micro-Nano Energy Technology and School of Physics and Optoelectronic, Xiangtan University, Hunan 411105, P.R. China
Xu Yijun
Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P.R. China
Liu Liping
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Bao Shiyun
Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China
Zhang Han
Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P.R. China
Two-dimensional black phosphorus (BP) has been demonstrated to be promising in photoelectronic devices, electrode materials, and biomedicine owing to its outstanding properties. However, the application of BP has been hindered by harsh preparation conditions, high costs, and easy degradation in ambient condition. Herein, we report a facile and cost-effective strategy for synthesis of orthorhombic phase BP and a kind of BP-reduced graphene oxide (BP/rGO) hybrids in which BP remains stable for more than 4 weeks ascribed to the formation of phosphorus-carbon covalent bonds between BP and rGO as well as the protection effect of the unique wrinkle morphology of rGO nanosheets. Surface modification BP/rGO hybrids (PEGylated BP/rGO) exhibit excellent photothermal performance with photothermal conversion efficiency as high as 57.79% at 808 nm. The BP/rGO hybrids exhibit enhanced antitumor effects both in vitro and in vivo, showing promising perspectives in biomedicine.
