Bacteriophages or “bacteria eaters” alternative to antibiotics, vaccine preparation and treatment of severe non-infectious diseases

Abstract

Bacteriophages are viruses with a simple structure that attack and kill bacteria, but like other more complex relatives they are perfect parasites that survive by infecting a host, in their case bacteria. Bacteriophages are among the most common and diverse organisms in the biosphere, ubiquitous where there are also bacteria. Without being harmful to macro organisms, bacteriophages can be found in ocean and sea water, soils, plants, animals, people, wastewater and food of animal origin contaminated by bacteria. It is believed that there are over 1.031 bacteriophages on earth. Currently, the expansion and intensification of the use of antibiotics has led to the increase of antibiotic resistance at the global level, and the focus of treatments on intestinal microecology has determined the intensification of research on its role in human health.

Keywords

• phage and bacterial lysis
• antibiotics and resistance
• gut microbiota
• phage display and vaccines