Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains

Shai Netser; Ana Meyer; Hen Magalnik; Asaph Zylbertal; Shani Haskal de la Zerda; Mayan Briller; Alexander Bizer; Valery Grinevich; Shlomo Wagner

doi:10.1038/s41467-020-19569-0

Nature Communications (Nov 2020)

Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains

Shai Netser,
Ana Meyer,
Hen Magalnik,
Asaph Zylbertal,
Shani Haskal de la Zerda,
Mayan Briller,
Alexander Bizer,
Valery Grinevich,
Shlomo Wagner

Affiliations

Shai Netser: Sagol Department of Neurobiology, the Integrated Brain and Behavior Research Center (IBBRC), University of Haifa
Ana Meyer: Department of Neuropeptide Research in Psychiatry, Central Institute of Mental Health, University of Heidelberg
Hen Magalnik: Sagol Department of Neurobiology, the Integrated Brain and Behavior Research Center (IBBRC), University of Haifa
Asaph Zylbertal: Department of Neuroscience, Physiology and Pharmacology, University College London
Shani Haskal de la Zerda: Sagol Department of Neurobiology, the Integrated Brain and Behavior Research Center (IBBRC), University of Haifa
Mayan Briller: Sagol Department of Neurobiology, the Integrated Brain and Behavior Research Center (IBBRC), University of Haifa
Alexander Bizer: Faculty of Natural Sciences, University of Haifa
Valery Grinevich: Department of Neuropeptide Research in Psychiatry, Central Institute of Mental Health, University of Heidelberg
Shlomo Wagner: Sagol Department of Neurobiology, the Integrated Brain and Behavior Research Center (IBBRC), University of Haifa

DOI: https://doi.org/10.1038/s41467-020-19569-0
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 19

Abstract

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Laboratory rat and mouse strains serve as animal models to explore brain mechanisms underlying social behavior. Here, the authors describe differences in social behavior between commonly used rat and mouse strains, which may reflect distinct dynamics of social motivation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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