Suspected Primary Intracranial Melanoma with Widespread Distant Metastases in a Cat

Abstract

An 8-year-old female Domestic Shorthair presented with signs of intracranial disease. Magnetic resonance imaging (MRI) of the head showed an extra-axial space-occupying mass within the cranial vault with a similar intensity lesion within the overlying temporalis muscle. Postmortem examination found masses within the head, lung, liver, spleen, and kidney consistent with malignant melanoma. Intracranial melanoma is rarely reported in cats and is typically only seen as a metastatic lesion associated with an ocular mass. Melanomas can be readily recognised on MRI as they are one of the few lesions which are hyperintense on T1-weighted images.

Keywords

• feline
• melanoma
• intracranial
• histopathology