Química Nova (Jul 2014)

Synthesis, characterization, and biological activity of a new class of dialkylphosphorylhydrazone derivatives of isatin

  • Letícia Silotti Zampirolli,
  • Marcela Jacques de Lemos,
  • Vinícius Tomaz Gonçalves,
  • Marco Andre Alves de Souza,
  • Sonia Regina de Souza,
  • Victor Marcos Rumjanek,
  • João Batista Neves DaCosta

DOI
https://doi.org/10.5935/0100-4042.20140162
Journal volume & issue
Vol. 37, no. 6
pp. 989 – 995

Abstract

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Sixteen dialkylphosphorylhydrazones were synthesized by condensation of phosphorylhydrazines with substituted isatins. Products were characterized by FTIR, ¹H-NMR, 13C-NMR, and 31P-NMR. Fungicidal activities of these compounds against Rhizoctonia solani and Fusarium oxysporum were also evaluated. Some compounds inhibited the growth of Rhizoctonia solani and Fusarium oxysporum by 43% and 51%, respectively. These compounds exhibited no effects on germination of lettuce seeds (Lactuca sativa L).

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