Anterior migration of dexamethasone implant in a pseudophakic patient with intact posterior capsule

Abstract

Intravitreal application of Ozurdex ® (Allergan, Inc., Irvine, CA, USA) which is a biodegradable, sustained-release dexamethasone implant has been reported to be effective in the treatment of macular edema. Migration of such implant into the anterior chamber has been recently described in cases without perfect zonular or the posterior capsular integrity. Herein, we report the first case with anterior migration of Ozurdex ® implant that mislocated just behind the intraocular lens (IOL) in an intact capsular bag. It is thought that such implant migrated anteriorly towards into the posterior chamber through weak zonules as the present case had a medical history of uneventful phacoemulsification surgery with the implantation of posterior chamber IOL. However, the migrated implant was well tolerated since there was no sign of the corneal complication, rise in intraocular pressure, and anterior chamber reaction. Close follow-up was scheduled to find out any signs of anterior segment pathology. Meanwhile dexamethasone implant completely degraded at the 4 th month of postoperative follow-up.

Keywords

• Fixed corneal compensation
• glaucoma
• retinal nerve fiber layer
• scanning laser polarimetry
• Exotropia
• recurrence
• surgery
• Choroid
• choroidal thickness
• enhanced depth imaging
• Cataract
• contrast sensitivity function
• filter
• orange
• visual acuity
• yellow
• High-risk factor
• p53
• retinoblastoma
• Central corneal thickness
• diurnal variation
• glaucoma
• intra-ocular pressure
• pseudoexfoliation syndrome
• Factors affecting visual outcome in traumatic cataracts
• primary posterior capsulotomy
• traumatic cataract
• visual outcome
• Calibration error
• calibration
• goldmann applanation tonometer
• Anterior migration
• Ozurdex
• posterior chamber