The Problems of Current Vaccinology

Abstract

The article describes the possible causes of the unpredictable reactions of child’s organism on vaccination and development of severe postvaccinal complications: epidemiological (uncontrolled group of children born from HIV-positive mothers and removed from the register upon reaching 18 monthes, and reduction in the selective pressure of contagious infectious diseases on human); genetic (lack of control and screening over the process of gene polymorphism, and the accumulation of point mutations); ignoring the immunological phenomena (antigenic imprinting and antibody-dependent amplification of infection).

Keywords

• vaccination
• HIV/AIDS
• immunological imprinting
• antibody-dependent amplification of infection