Nature Communications (May 2021)
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
- Arvind Gharbharan,
- Carlijn C. E. Jordans,
- Corine GeurtsvanKessel,
- Jan G. den Hollander,
- Faiz Karim,
- Femke P. N. Mollema,
- Janneke E. Stalenhoef – Schukken,
- Anthonius Dofferhoff,
- Inge Ludwig,
- Adrianus Koster,
- Robert-Jan Hassing,
- Jeannet C. Bos,
- Geert R. van Pottelberge,
- Imro N. Vlasveld,
- Heidi S. M. Ammerlaan,
- Elena M. van Leeuwen – Segarceanu,
- Jelle Miedema,
- Menno van der Eerden,
- Thijs J. Schrama,
- Grigorios Papageorgiou,
- Peter te Boekhorst,
- Francis H. Swaneveld,
- Yvonne M. Mueller,
- Marco W. J. Schreurs,
- Jeroen J. A. van Kampen,
- Barry Rockx,
- Nisreen M. A. Okba,
- Peter D. Katsikis,
- Marion P. G. Koopmans,
- Bart L. Haagmans,
- Casper Rokx,
- Bart J. A. Rijnders
Affiliations
- Arvind Gharbharan
- Erasmus MC, University Medical Center
- Carlijn C. E. Jordans
- Erasmus MC, University Medical Center
- Corine GeurtsvanKessel
- Erasmus MC, University Medical Center
- Jan G. den Hollander
- Maasstad Hospital
- Faiz Karim
- Groene Hart Hospital
- Femke P. N. Mollema
- Haaglanden Medical Center
- Janneke E. Stalenhoef – Schukken
- OLVG Hospital
- Anthonius Dofferhoff
- Canisius Wilhelmina Hospital
- Inge Ludwig
- Bernhoven Hospital
- Adrianus Koster
- Viecuri Medical Center
- Robert-Jan Hassing
- Rijnstate Hospital
- Jeannet C. Bos
- Reinier de Graaf Gasthuis
- Geert R. van Pottelberge
- ZorgSaam Hospital
- Imro N. Vlasveld
- Martini Hospital
- Heidi S. M. Ammerlaan
- Catharina Hospital
- Elena M. van Leeuwen – Segarceanu
- Sint Antonius Hospital
- Jelle Miedema
- Erasmus MC, University Medical Center
- Menno van der Eerden
- Erasmus MC, University Medical Center
- Thijs J. Schrama
- Erasmus MC, University Medical Center
- Grigorios Papageorgiou
- Erasmus MC, University Medical Center
- Peter te Boekhorst
- Erasmus MC, University Medical Center
- Francis H. Swaneveld
- Unit of Transfusion Medicine, Sanquin Blood Supply
- Yvonne M. Mueller
- Erasmus MC, University Medical Center
- Marco W. J. Schreurs
- Erasmus MC, University Medical Center
- Jeroen J. A. van Kampen
- Erasmus MC, University Medical Center
- Barry Rockx
- Erasmus MC, University Medical Center
- Nisreen M. A. Okba
- Erasmus MC, University Medical Center
- Peter D. Katsikis
- Erasmus MC, University Medical Center
- Marion P. G. Koopmans
- Erasmus MC, University Medical Center
- Bart L. Haagmans
- Erasmus MC, University Medical Center
- Casper Rokx
- Erasmus MC, University Medical Center
- Bart J. A. Rijnders
- Erasmus MC, University Medical Center
- DOI
- https://doi.org/10.1038/s41467-021-23469-2
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 12
Abstract
There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 300 mL convalescent plasma.
