Energy potential of mitochondria under led lighting and risks of eyes diseases

Abstract

Disorders in refraction, myopia and other eye disorders lead to a decrease in efficiency of any activity and impose certain limitations on educational and working capabilities of economically active population. As light denaturation grows, fatigue caused by performing test visual efforts also increases. The lowest decrease in physiological and mental parameters occurs when a person works under natural luminance, and the greatest one, under completely artificial luminance. Artificial light sources, as opposed to an even sunlight spectrum, have peaks and notches in photon flow under specific wave lengths. It is shown in the paper that a drastic decrease in spectral-energy characteristics occurs in red light area with wave length 670 nm as compared to sunlight spectrum. The authors consider how 670 nm red light deficiency influences visual analyzer cells and mitochondria in particular. A theory that focuses on mitochondria aging states that oxidative stress caused by DNA mutations in mitochondria is associated with a decrease in adenosine triphosphate (ATP) production leading to cell degeneration. A rate at which this degradation develops is related to metabolic demands of a body, progressing inflammation in the outer retina, macrophages penetration and cells loss; as a result, eye sight deteriorates. A mechanism of a decrease in efficiency of ATP-synthesizing structures is examined within "670 nm light – water structural properties – efficiency of mitochondria rotary engine operations" cause-and-effect chain. The authors substantiate the necessity to synthesize red 670 nm luminopfor and to optimize LED lighting in this spectrum area.

Keywords

• red 670 nm light
• water structure
• atp synthesis efficiency
• energy potential of mitochondria