p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers

Ioulia Chatzistamou; Nikolina Dioufa; George Trimis; Alexandra Sklavounou; Christos Kittas; Hippokratis Kiaris; Athanasios G. Papavassiliou

doi:10.3233/ACP-CLO-2010-0528

Analytical Cellular Pathology (Jan 2010)

p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers

Ioulia Chatzistamou,
Nikolina Dioufa,
George Trimis,
Alexandra Sklavounou,
Christos Kittas,
Hippokratis Kiaris,
Athanasios G. Papavassiliou

Affiliations

Ioulia Chatzistamou: Department of Basic Sciences, Dental School, University of Athens, Athens, Greece
Nikolina Dioufa: Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
George Trimis: Department of Oral Medicine and Pathology, Dental School, University of Athens, Athens, Greece
Alexandra Sklavounou: Department of Oral Medicine and Pathology, Dental School, University of Athens, Athens, Greece
Christos Kittas: Department of Histology–Embryology, Medical School, University of Athens, Athens, Greece
Hippokratis Kiaris: Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece
Athanasios G. Papavassiliou: Department of Biological Chemistry, Medical School, University of Athens, Athens, Greece

DOI: https://doi.org/10.3233/ACP-CLO-2010-0528
Journal volume & issue: Vol. 33, no. 1
pp. 19 – 26

Abstract

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Background: Concerted alterations between stromal fibroblasts and neoplastic cells underline the carcinogenic process. Activation of alpha-smooth muscle actin (SMA) expression, a cytoskeleton protein normally expressed only in myoepithelial cells, is considered a landmark for the activation of stromal fibroblasts with little however being known regarding the mechanism governing the expression of SMA in the stroma.

Published in Analytical Cellular Pathology

ISSN: 2210-7177 (Print); 2210-7185 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Science: Biology (General): Cytology
Website: https://onlinelibrary.wiley.com/journal/2641

About the journal