Nature Communications (Apr 2018)
Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese
Abstract
Recent natural selection left signals in human genomes. Here, Okada et al. generate high-depth whole-genome sequence (WGS) data (25.9×) from 2,234 Japanese people of the BioBank Japan Project (BBJ), and identify signals of recent natural selection which overlap variants associated with human traits.