Infection and Drug Resistance (Oct 2022)
Study on the Detection and Infection Distribution of Multidrug-Resistant Organisms in Different Specimens
Abstract
Zhanjie Li,1 Ying Zhang,2 Weihong Zhang,1 Yongxiang Zhang,1 Suming Zhou,3 Wensen Chen,1 Yun Liu4,5 1Department of Infection Control, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 2Department of Infection Control, Lianshui County People’s Hospital, Huaian, People’s Republic of China; 3Department of Geriatric Critical Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 4Department of Information, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China; 5Department of Medical Informatics, School of BioMedical Engineering and Informatics, Nanjing Medical University, Nanjing, People’s Republic of ChinaCorrespondence: Wensen Chen, Department of Infection Control, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China, Tel +86-13809049855, Email [email protected] Yun Liu, Department of Information, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guang Zhou Road, Nanjing, People’s Republic of China, Tel +86-18805152008, Email [email protected]: To analyze the infection and distribution of multidrug-resistant organisms (MDRO) in different clinical specimens, thereby providing a reference for clinical diagnosis and treatment and prevention and control.Patient and Methods: 2314 strains of MDRO isolated from clinical specimens in the First Affiliated Hospital of Nanjing Medical University from January to December 2020. MDRO were collected by Information System. The detection rate of MDRO, infection rate, the proportion of infection, and detection rate of MDRO infection in different specimens were analyzed.Results: The top three specimens in the detection rate of MDRO were BALF (60.71%), sputum (33.68%), and blood (28.79%). The top three specimens in the proportion of MDRO infection were blood (97.74), other sterile body fluids (90.35%), and BALF (90.20%). The top three specimens in the MDRO infection rate were BALF (9.75%), sputum (3.07%), and secretions (2.90%). The top three specimens in the detection rate of MDRO infection were sputum (0.63‰), other sterile body fluids (0.13‰), and secretions (0.11‰).Conclusion: The detection and infection distribution of MDRO vary greatly in different specimens. The submission of sterile body fluids for examination should be strengthened and the standard of sample collection should be highlighted.Keywords: different specimens, MDRO, detection rate, infection, sterile body fluids
