Cancers (Feb 2022)

Particle Therapy for Breast Cancer

  • Roman O. Kowalchuk,
  • Kimberly S. Corbin,
  • Rachel B. Jimenez

DOI
https://doi.org/10.3390/cancers14041066
Journal volume & issue
Vol. 14, no. 4
p. 1066

Abstract

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Particle therapy has received increasing attention in the treatment of breast cancer due to its unique physical properties that may enhance patient quality of life and reduce the late effects of therapy. In this review, we will examine the rationale for the use of proton and carbon therapy in the treatment of breast cancer and highlight their potential for sparing normal tissue injury. We will discuss the early dosimetric and clinical studies that have been pursued to date in this domain before focusing on the remaining open questions limiting the widespread adoption of particle therapy.

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