Modeling the evolution of cells outgrowth due to the force exerted by actins

Abstract

Motility and membrane deformation are crucial to motile cells. Therefore formation of protrusion in the membrane has been the subject of various studies. The stable shape of the membrane and also its movements are controlled by the forces exerted by actin filaments. In order to study the protrusion behavior, we represented a toy model based on actin filaments polar characteristic and elastic characteristic of the membrane. We also studied the effect of changing physical parameters such as filament density, the membrane tension, and the polymerization rate on the shape and the magnitude of the protrusion.

Keywords

• protrusion
• membrane deformation
• actin filament
• semi-flexible region
• gel