Journal of Indian Society of Periodontology (Jan 2009)

Gene therapy and its implications in Periodontics

  • Mahale Swapna,
  • Dani Nitin,
  • Ansari Shumaila,
  • Kale Triveni

Journal volume & issue
Vol. 13, no. 1
pp. 1 – 5

Abstract

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Gene therapy is a field of Biomedicine. With the advent of gene therapy in dentistry, significant progress has been made in the control of periodontal diseases and reconstruction of dento-alveolar apparatus. Implementation in periodontics include: -As a mode of tissue engineering with three approaches: cell, protein-based and gene delivery approach. -Genetic approach to Biofilm Antibiotic Resistance. Future strategies of gene therapy in preventing periodontal diseases: -Enhances host defense mechanism against infection by transfecting host cells with an antimicrobial peptide protein-encoding gene. -Periodontal vaccination. Gene therapy is one of the recent entrants and its applications in the field of periodontics are reviewed in general here.

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