Aura and osmophobia are associated with the <i>IL1A</i> -889C &gt; T (rs1800587) variant in migraine

Abstract

Background Migraine belongs to the group of primary headaches, affecting 14.4% of the global population. The pathophysiological mechanisms of migraine involve the interplay between hypothalamic activation, cortical spreading depression, trigeminal stimulation, and inflammatory components with neurogenic inflammation or neuroinflammation.

Keywords

• Headache
• Migraine Disorders
• Interleukin-1alpha
• Genetic Variation
• Cefaleia
• Transtornos de Enxaqueca
• Interleucina-1alfa
• Variação Genética