Research Progress in Pharmacological Effects and Mechanisms of <i>Angelica sinensis</i> against Cardiovascular and Cerebrovascular Diseases
Linlin Chen,
Bei Fan,
Fengzhong Wang,
Yang Song,
Xizhi Wang,
Ying Meng,
Yumin Chen,
Qing Xia,
Jing Sun
Affiliations
Linlin Chen
School of Management, Liaoning University of International Business and Economics, Dalian 116052, China
Bei Fan
Risk Assessment Laboratory of Agricultural Products Processing Quality and Safety, Key Laboratory of Agricultural Products Quality and Safety Collection, Storage and Transportation Control, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China
Fengzhong Wang
Risk Assessment Laboratory of Agricultural Products Processing Quality and Safety, Key Laboratory of Agricultural Products Quality and Safety Collection, Storage and Transportation Control, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China
Yang Song
School of Management, Liaoning University of International Business and Economics, Dalian 116052, China
Xizhi Wang
School of Management, Liaoning University of International Business and Economics, Dalian 116052, China
Ying Meng
School of Management, Liaoning University of International Business and Economics, Dalian 116052, China
Yumin Chen
School of Management, Liaoning University of International Business and Economics, Dalian 116052, China
Qing Xia
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250013, China
Jing Sun
School of Management, Liaoning University of International Business and Economics, Dalian 116052, China
Angelica sinensis (Oliv.) Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is commonly used for the prevention and treatment of cardiovascular and cerebrovascular diseases in the elderly, especially in improving ischemic damage to the heart and brain, protecting vascular cells, and regulating inflammatory reactions. This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. It provides a new reference direction for the in-depth research and application of A. sinensis in the prevention, improvement, and treatment of cardiovascular and cerebrovascular diseases.
