Future Natural Products (Nov 2022)

The effect of aqueous extract of black radish root on urine pH in stone-forming patients: A single blind clinical trial

  • Majid Shirani,
  • Zahra Vasei,
  • Morteza Sedehi,
  • Sareh Mohammadi,
  • Elham Bijad,
  • Solomon Habtemariam,
  • Mohammad Rahimi–Madiseh,
  • Zahra Lorigooini

DOI
https://doi.org/10.34172/fnp.2022.07
Journal volume & issue
Vol. 8, no. 2
pp. 30 – 34

Abstract

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Background and aims: Given the prevalence of urolithiasis and the popularity of black radish extract for the treatment of this problem, the present study was designed to investigate its effect in alkalizing urine in stone-forming patients referred to Imam Ali clinic in Shahrekord (Iran). Methods: In this clinical trial, the urine pH was measured along with the 24-hour urine assessment for urine volume and urine citrate, oxalate, calcium, uric acid, and creatinine levels of 20 patients before and after the intervention. Results: The results showed a significant increase (P 0.05). Conclusion: Raphanus sativus extract treatment can increase urine pH, urine citrate level, and urine volume and decreases uric acid and oxalate levels. Therefore, the plant may be used for the treatment and prevention of uric acid and cystine stones.

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