Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-γ-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site

• Cory T. Reidl,
• Romila Mascarenhas,
• Thahani S. Habeeb Mohammad,
• Marlon R. Lutz,
• Pei W. Thomas,
• Walter Fast,
• Dali Liu,
• Daniel P. Becker

Affiliations

Cory T. Reidl

Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, United States

Romila Mascarenhas

Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, United States

Thahani S. Habeeb Mohammad

Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, United States

Marlon R. Lutz

Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, United States

Pei W. Thomas

Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin, Austin, Texas, United States

Walter Fast

Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin, Austin, Texas, United States

Dali Liu

Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, United States

Daniel P. Becker

Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, United States