Geographical Distribution of Breast Cancer in Hamadan Province during 2008-2015 Using Bayesian Method

Abstract

Background and Objectives: Breast cancer has the highest incidence in the Iranian women. Methods: A cross-sectional study was conducted. All female with breast cancer during 2008-2015 were enrolled. Breast cancer registration is based on the pathology method in Iran. The information about female with breast cancer was collected from their files in the cancer registry department of Hamadan Health Center. The samples were divided into four groups according to age ( 50) and location (city, village). GeoBUGS was used to generate a map of high-risk areas in Hamedan Province based on the adjusted relative risk estimate (RR*) in OpenBUGS v 3.2.3 software. Results: This study included 1316 females with breast cancer. The mean age of the patients was 50.38±12.98 years. The results of the study showed that high-risk areas of breast cancer for were Assadabad urban females aged over 50 years (RR*(i)=1.32, CI= 0.99,1.79) and Tuyserkan (RR*(i)=1.09, CI= 1.08,1.38) and Razan (RR*(i)=1.09, CI= 0.85,1.40) for females below 50 years. In addition, Razan for rural females over 50 years old (RR*(i)=1.18, CI=0.82,1.73) and Malayer for females below 50 years old (RR*(i)=1.08, CI= 0.81,1.45) were high risk areas for breast cancer in Hamadan Province. Conclusion: The distribution of breast cancer is different at different ages and in the cities of Hamadan Province. Asadabad, Tuyserkan, Razan and Malayer were high risk areas for breast cancer in Hamadan Province.

Keywords

• breast cancer
• bayes
• disease mapping
• hamedan
• openbugs
• incidence