Molecules (Mar 2007)

Syntheses and Biological Activities of 6-Aryl-3-(3-hydroxy- propyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines

  • Hai-le Zhang,
  • An-jiang Zhang,
  • Xian-xing Chen,
  • Jian-yu Jin,
  • Li-xue Zhang

DOI
https://doi.org/10.3390/12030297
Journal volume & issue
Vol. 12, no. 3
pp. 297 – 303

Abstract

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A series of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]-thia-diazines were synthesized by the reaction of 4-amino-3-(3-hydroxypropyl)-5-mercapto-1,2,4-triazole (1) with substituted ω-haloacetophenones. Their structures were confirmed by elemental analysis, IR, 1H-NMR, and 13C-NMR. Tests of plant growth regulating effects showed that the title compounds display remarkable inhibitory activities on the growth of radish and wheat.

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