共轭亚油酸的生理活性及制备方法研究进展Progress on the physiological activity and preparation methods of conjugated linoleic acid

Abstract

旨在为进一步提高共轭亚油酸产量提供理论依据，总结概述了共轭亚油酸的生理活性与制备方法的研究进展。共轭亚油酸是一种天然存在于反刍动物体内的物质，具有降低胆固醇含量、抗癌、抗氧化、提高免疫力等重要生理功能，在减肥、癌症治疗、哮喘治疗等方面发挥了重要作用，在功能性膳食研发领域拥有巨大潜力。由于共轭亚油酸的天然含量与来源无法满足人们日常生活的需求，因此研究更高产率的共轭亚油酸的合成方法一直是热点内容。合成共轭亚油酸的方法主要有生物合成法和化学合成法，生物合成法中的微生物合成法和酶催化异构化合成法是近年来的研究热点。 The research progress on the physiological activity and preparation methods of conjugated linoleic acid were summarized and outlined to provide a theoretical basis for further improving the yield of conjugated linoleic acid. Conjugated linoleic acid is a substance naturally existing in ruminants and has important physiological functions such as reducing the contents of cholesterol in the body, anti-cancer, antioxidant and immune enhancement, and plays an important role in weight loss, cancer treatment and asthma disease treatment, and has great potential in the field of functional diet research and development. Since the natural content and source of conjugated linoleic acid can not meet the needs of people′s daily life, the research on the synthesis of conjugated linoleic acid with higher yield has been a hot topic. The main methods for the synthesis of conjugated linoleic acid includ biological synthesis and chemical synthesis. Among biological synthesis, microbial synthesis and enzymatic isomerization synthesis are the research focuses in recent years.

Keywords

• 共轭亚油酸;生理活性;制备
• conjugated linoleic acid; physiological activity; preparation