Electroacupuncture inhibits the expression of HMGB1/RAGE and alleviates injury to the primary motor cortex in rats with cerebral ischemia

Nie Zeyin; Miao Huachun; Li Chenyu; Wu Feng

doi:10.1515/tnsci-2022-0316

Translational Neuroscience (Oct 2023)

Electroacupuncture inhibits the expression of HMGB1/RAGE and alleviates injury to the primary motor cortex in rats with cerebral ischemia

Nie Zeyin,
Miao Huachun,
Li Chenyu,
Wu Feng

Affiliations

Nie Zeyin: Department of Human Anatomy, Wannan Medical College, No. 22, Wenchang West Road, Wuhu, 241002, Anhui, China
Miao Huachun: Department of Human Anatomy, Wannan Medical College, No. 22, Wenchang West Road, Wuhu, 241002, Anhui, China
Li Chenyu: Department of Human Anatomy, Wannan Medical College, No. 22, Wenchang West Road, Wuhu, 241002, Anhui, China
Wu Feng: Department of Human Anatomy, Wannan Medical College, No. 22, Wenchang West Road, Wuhu, 241002, Anhui, China

DOI: https://doi.org/10.1515/tnsci-2022-0316
Journal volume & issue: Vol. 14, no. 1
pp. 1457 – 64

Abstract

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The high-mobility group box 1 (HMGB1)/receptor for advanced glycation end products (RAGE) signaling pathway holds promise as a potential therapeutic target for ischemic brain injury. The effects of FPS-ZM1 and electroacupuncture (EA) on activation of the HMGB1/RAGE signaling pathway after cerebral ischemia remain uncertain.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

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