Quantitative Magnetic Resonance Imaging for Biological Image-Guided Adaptive Radiotherapy

Petra J. van Houdt; Yingli Yang; Uulke A. van der Heide

doi:10.3389/fonc.2020.615643

Frontiers in Oncology (Jan 2021)

Quantitative Magnetic Resonance Imaging for Biological Image-Guided Adaptive Radiotherapy

Petra J. van Houdt,
Yingli Yang,
Uulke A. van der Heide

Affiliations

Petra J. van Houdt: Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands
Yingli Yang: Department of Radiation Oncology, University of California, Los Angeles, CA, United States
Uulke A. van der Heide: Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands

DOI: https://doi.org/10.3389/fonc.2020.615643
Journal volume & issue: Vol. 10

Abstract

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MRI-guided radiotherapy systems have the potential to bring two important concepts in modern radiotherapy together: adaptive radiotherapy and biological targeting. Based on frequent anatomical and functional imaging, monitoring the changes that occur in volume, shape as well as biological characteristics, a treatment plan can be updated regularly to accommodate the observed treatment response. For this purpose, quantitative imaging biomarkers need to be identified that show changes early during treatment and predict treatment outcome. This review provides an overview of the current evidence on quantitative MRI measurements during radiotherapy and their potential as an imaging biomarker on MRI-guided radiotherapy systems.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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Abstract

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