PLoS ONE (Jan 2013)

Association between prostate cancer and urinary calculi: a population-based study.

  • Shiu-Dong Chung,
  • Shih-Ping Liu,
  • Herng-Ching Lin

DOI
https://doi.org/10.1371/journal.pone.0057743
Journal volume & issue
Vol. 8, no. 2
p. e57743

Abstract

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BackgroundUnderstanding the reasons underlying the emerging trend and the changing demographics of Asian prostate cancer (PC) has become an important field of study. This study set out to explore the possibility that urinary calculi (UC) and PC may share an association by conducting a case-control study on a population-based database in Taiwan.MethodsThe cases of this study included 2,900 subjects ≥ 40 years-old who had received their first-time diagnosis of PC and 14,500 randomly selected controls without PC. Conditional logistic regressions were employed to explore the association between PC and having been previously diagnosed with UC.ResultsWe found that prior UC was found among 608 (21.0%) cases and 2,037 (14.1%) controls (pConclusionsThis investigation detected an association between PC and prior UC. These results highlight a potential target population for PC screening.