Детские инфекции (Москва) (Sep 2015)

ESTIMATION OF MOLECULES OF AVERAGE AND LOW MASS, PEPTIDES OF SERUM IN INFANTS WITH PNEUMONIA AND ARVI

  • S. S. Shevchenko,
  • A. I. Grekova

DOI
https://doi.org/10.22627/2072-8107-2015-14-1-9-12
Journal volume & issue
Vol. 14, no. 1
pp. 9 – 12

Abstract

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Metabolic disorders lead to admission into the bloodstream of a large number of toxic substances medium molecular weight, the concentration of which increases in respiratory diseases. Objective: determine the level of molecules of average and low mass, peptides in the serum of in infants with pneumonia and ARVI. Determination of the level of molecules of average and low weight, and the content of the peptides in the serum was performed screening methodin infantswith pneumonia (31 children) and ARVI (37 children). There were 20 healthy children in control groupof the same age.In the acute period of the disease the level MSINM and peptides was significantly increased as in pneumonia, and ARVI. The highest values were observed during the study content of peptides. In addition to a clear dependence of the concentration of MSINM and peptides from the severity of infectious toxicosis found a significant difference between these parameters when comparing toxic syndrome with pneumonia and ARVI. Parameters of MSINM and peptides can be used as diagnostic criteria of pneumonia, ARVI and intensity of infection toxicosis.

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