BMC Cancer (Aug 2021)

Preferences of first-degree relatives of gastric cancer patients for gastric cancer screening: a discrete choice experiment

  • Hui-qin Li,
  • Hui Xue,
  • Hua Yuan,
  • Guang-ying Wan,
  • Xiu-ying Zhang

DOI
https://doi.org/10.1186/s12885-021-08677-9
Journal volume & issue
Vol. 21, no. 1
pp. 1 – 11

Abstract

Read online

Abstract Background It is very necessary to implement gastric cancer screening in China to reduce the mortality of gastric cancer, but there are no national screening guidelines and programs. Understanding of individual preferences is conducive to formulating more acceptable screening strategies, and discrete choice experiments can quantify individual preferences. In addition, the first-degree relatives of gastric cancer patients are at high risk for gastric cancer. Compared with those without a family history of gastric cancer, the risk of gastric cancer in first-degree relatives of gastric cancer patients is increased by 60%. Therefore, a discrete choice experiment was carried out to quantitatively analyse the preferences of first-degree relatives of gastric cancer patients for gastric cancer screening to serve as a reference for the development of gastric cancer screening strategies. Methods A questionnaire was designed based on a discrete choice experiment, and 342 first-degree relatives of gastric cancer patients were investigated. In STATA 15.0 software, the data were statistically analysed using a mixed logit model. Results The five attributes included in our study had a significant influence on the preferences of first-degree relatives of gastric cancer patients for gastric cancer screening (P < 0.05). Participants most preferred the sensitivity of the screening program to be 95% (coefficient = 1.424, P < 0.01) with a willingness to pay 2501.902 Yuan (95% CI, 738.074–4265.729). In addition, the participants’ sex and screening experiences affected their preferences. An increase in sensitivity 35 to 95% had the greatest impact on the participants’ willingness to choose a gastric cancer screening program. Conclusion The formulation of gastric cancer screening strategies should be rooted in people’s preferences. The influence of sex differences and screening experiences on the preferences of people undergoing screening should be considered, and screening strategies should be formulated according to local conditions to help them play a greater role.

Keywords