Nature Communications (May 2019)

Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformans

  • P. M. Ashton,
  • L. T. Thanh,
  • P. H. Trieu,
  • D. Van Anh,
  • N. M. Trinh,
  • J. Beardsley,
  • F. Kibengo,
  • W. Chierakul,
  • D. A. B. Dance,
  • S. Rattanavong,
  • V. Davong,
  • L. Q. Hung,
  • N. V. V. Chau,
  • N. L. N. Tung,
  • A. K. Chan,
  • G. E. Thwaites,
  • D. G. Lalloo,
  • C. Anscombe,
  • L. T. H. Nhat,
  • J. Perfect,
  • G. Dougan,
  • S. Baker,
  • S. Harris,
  • J. N. Day

DOI
https://doi.org/10.1038/s41467-019-10092-5
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Cryptococcus neoformans is an opportunistic fungal pathogen which primarily affects people with immune defects including those living with HIV. Here, the authors sequence and analyze genomes of 699 isolates, and identify recent population expansion driven by three phylogenetic groups.