Emerging Infectious Diseases (Oct 2022)

Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

  • Sylvanus Okogbenin,
  • Cyril Erameh,
  • Joseph Okoeguale,
  • Osahogie Edeawe,
  • Esele Ekuaze,
  • Kelly Iraoyah,
  • John Agho,
  • Mirjam Groger,
  • Benno Kreuels,
  • Lisa Oestereich,
  • Femi O. Babatunde,
  • Peter Akhideno,
  • Stephan Günther,
  • Michael Ramharter,
  • Till Omansen

DOI
https://doi.org/10.3201/eid2810.220625
Journal volume & issue
Vol. 28, no. 10
pp. 2060 – 2063

Abstract

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Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.

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