Diagnostics (May 2024)
Neuroendocrine Breast Carcinoma: Interesting Images of an Underdiagnosed Entity
- Christoforos Kosmidis,
- Kassiani Boulogeorgou,
- Panagiota Roulia,
- Marios Dagher,
- Georgios Anthimidis,
- Georgios Petrakis,
- Charilaos Koulouris,
- Stylianos Mantalovas,
- Styliani Laskou,
- Vasiliki Magra,
- Vasileios Alexandros Karakousis,
- Christina Sevva,
- Eleni Paschou,
- Vasileios Stergios,
- Stylianos Kosmidis,
- Chrysi Maria Mystakidou,
- Vasiliki Theodorou,
- Nikolaos Iason Katsios,
- Triantafyllia Koletsa,
- Konstantinos Sapalidis,
- Isaak Kesisoglou
Affiliations
- Christoforos Kosmidis
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Kassiani Boulogeorgou
- Department of Pathology, School of Medicine, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece
- Panagiota Roulia
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Marios Dagher
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Georgios Anthimidis
- European Interbalkan Medical Center, 10 Asklipiou Street, 55535 Pylaia, Greece
- Georgios Petrakis
- Department of Pathology, School of Medicine, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece
- Charilaos Koulouris
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Stylianos Mantalovas
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Styliani Laskou
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Vasiliki Magra
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Vasileios Alexandros Karakousis
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Christina Sevva
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Eleni Paschou
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Vasileios Stergios
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Stylianos Kosmidis
- Department of Medicine, Medical University of Plovdiv, y.B.Apo15A, 4002 Plovdiv, Bulgaria
- Chrysi Maria Mystakidou
- Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
- Vasiliki Theodorou
- Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
- Nikolaos Iason Katsios
- Faculty of Health Sciences, Medical School, University of Ioannina, 45110 Ioannina, Greece
- Triantafyllia Koletsa
- Department of Pathology, School of Medicine, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece
- Konstantinos Sapalidis
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- Isaak Kesisoglou
- 3rd Surgical Department, University General Hospital of Thessaloniki “AHEPA”, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
- DOI
- https://doi.org/10.3390/diagnostics14111133
- Journal volume & issue
-
Vol. 14,
no. 11
p. 1133
Abstract
Breast cancer is the most common type of cancer of the female gender. A rare subtype of breast cancer is the invasive breast carcinoma (IBC) with neuroendocrine (NE) differentiation. Its incident is believed to be 0.1% to 5% of all breast cancers. We report a rare case of a 66-year old woman who presented with an isolated nodule of the left breast. The patient underwent modified radical mastectomy. Pathology revealed invasive breast carcinoma with neuroendocrine differentiation. Invasive breast carcinoma is an extremely rare group of neoplasms, the exact frequency of which cannot be determined with current data. Therefore, it is necessary for future studies to focus on the pathophysiology of this subtype of breast cancer and on the potential therapeutic approaches.
Keywords