Cerebral metabolic mechanisms of migraine

Abstract

Migraine is one of the most common primary headaches, but its pathogenesis remains unclear. Recent studies have found that the onset of migraine may be a response to the imbalance of brain energy metabolism and oxidative stress, suggesting that migraine may be a metabolic disease of brain related to mitochondrial dysfunction. This study uses the migraine trigger and mitigating factors, biological markers, genetic research and evidence⁃based treatment as the breakthrough point, to explore the pathogenesis of migraine brain energy metabolism, and explores the mechanism of brain energy metabolism and other associated with migraine mechanism, in order to provide a new strategy for the treatment of migraine and promote the development of the individual and precise treatment of migraine.

Keywords

• migraine
• energy metabolism
• mitochondria
• calcitonin gene ⁃ related peptide
• review