One Approach for Dynamic L-lysine Modelling of Repeated Fed-batch Fermentation

Abstract

This article deals with establishment of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-lysine production. The presented approach of the investigation includes the following main procedures: description of the process by generalized stoichiometric equations; preliminary data processing and calculation of specific rates for main kinetic variables; identification of the specific rates as a second-order non-linear dynamic models; establishment and optimisation of dynamic model of the process; simulation researches. MATLAB is used as a research environment.

Keywords

• Modelling
• Optimisation
• Repeated fed-batch process
• Fed-batch process with droppings
• L-lysine