Breast Cancer: Targets and Therapy (Feb 2019)
Breast cancer risk in a rapidly aging population: advances and approaches to study the aging tissue microenvironment
Abstract
Steven J GrecoDepartment of Medicine, Division of Hematology and Oncology, Rutgers-New Jersey Medical School, Newark, NJ, USAAging is the predominant risk factor for most chronic diseases, and is the primary cause of morbidity and mortality in the developed world. The rapidly increasing rate of global aging poses significant economic concern to the current health care model. A better understanding of the biology of aging is necessary to yield new approaches that extend the human “health span” and delay the onset of age-related disease. These approaches would address the underlying mechanisms of disease, rather than treat their symptoms individually.