Nature Communications (May 2018)
Regulatory protein SrpA controls phage infection and core cellular processes in Pseudomonas aeruginosa
- Jiajia You,
- Li Sun,
- Xiaojing Yang,
- Xuewei Pan,
- Zhiwei Huang,
- Xixi Zhang,
- Mengxin Gong,
- Zheng Fan,
- Lingyan Li,
- Xiaoli Cui,
- Zhaoyuan Jing,
- Shouguang Jin,
- Zhiming Rao,
- Weihui Wu,
- Hongjiang Yang
Affiliations
- Jiajia You
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Li Sun
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Xiaojing Yang
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Xuewei Pan
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Zhiwei Huang
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Xixi Zhang
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Mengxin Gong
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Zheng Fan
- Department of Microbiology, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, College of Life Sciences, Nankai University
- Lingyan Li
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Xiaoli Cui
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Zhaoyuan Jing
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- Shouguang Jin
- Department of Microbiology, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, College of Life Sciences, Nankai University
- Zhiming Rao
- The Key Laboratory of Industrial Biotechnology, Ministry of Education, Laboratory of Applied Microorganisms and Metabolic Engineering, School of Biotechnology, Jiangnan University
- Weihui Wu
- Department of Microbiology, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, College of Life Sciences, Nankai University
- Hongjiang Yang
- State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology of the Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology
- DOI
- https://doi.org/10.1038/s41467-018-04232-6
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 14
Abstract
You et al. show that SrpA, a small protein widely conserved among bacteria, controls core cellular processes in response to phage infection and environmental signals in Pseudomonas aeruginosa, including cell motility, chemotaxis, biofilm formation, and virulence.
