Gold Nanospikes Formation on Screen-Printed Carbon Electrode through Electrodeposition Method for Non-Enzymatic Electrochemical Sensor
Isa Anshori,
Raih Rona Althof,
Lavita Nuraviana Rizalputri,
Eduardus Ariasena,
Murni Handayani,
Arfat Pradana,
Mohammad Rizki Akbar,
Mas Rizky Anggun Adipurna Syamsunarno,
Agnes Purwidyantri,
Briliant Adhi Prabowo,
Muhammad Sjahrul Annas,
Hasim Munawar,
Brian Yuliarto
Affiliations
Isa Anshori
Lab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of Technology, Bandung 40132, Indonesia
Raih Rona Althof
Lab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of Technology, Bandung 40132, Indonesia
Lavita Nuraviana Rizalputri
Lab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of Technology, Bandung 40132, Indonesia
Eduardus Ariasena
Lab-on-Chip Group, Biomedical Engineering Department, Bandung Institute of Technology, Bandung 40132, Indonesia
Murni Handayani
National Research and Innovation Agency (BRIN), Tangerang Selatan 15314, Indonesia
Arfat Pradana
Research Center for Nanoscience and Nanotechnology (RCNN), Bandung Institute of Technology, Bandung 40132, Indonesia
Mohammad Rizki Akbar
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Padjadjaran and Dr. Hasan Sadikin General Hospital, Bandung 40161, Indonesia
Mas Rizky Anggun Adipurna Syamsunarno
Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung 45363, Indonesia
Agnes Purwidyantri
School of Chemistry and Chemical Engineering, Queen’s University Belfast, Belfast BT7 1NN, UK
Briliant Adhi Prabowo
School of Mathematics and Physics, Queen’s University Belfast, Belfast BT7 1NN, UK
Muhammad Sjahrul Annas
Mechanical Engineering Department, Trisakti University, Jakarta 11440, Indonesia
Hasim Munawar
PT Mitra Asiatek Biosensor, Jakarta 12520, Indonesia
Brian Yuliarto
Research Center for Nanoscience and Nanotechnology (RCNN), Bandung Institute of Technology, Bandung 40132, Indonesia
In this study, we reported the construction of Gold Nanospike (AuNS) structures on the surface of screen-printed carbon electrode (SPCE) used for non-enzymatic electrochemical detection. This modification was prepared with a one-step electrodeposition method by controlling the electrodeposition parameters, such as applied potential and deposition time, via Constant Potential Amperometry (CPA). Those parameters and precursor solution concentration were varied to investigate the optimum electrodeposition configuration. The results confirmed that AuNS were homogenously deposited and well-dispersed on the working electrode surface of SPCE. The AuNS-modified SPCE was implemented as a non-enzymatic sensor toward dopamine and could enhance the electrocatalytic ability compared with the bare SPCE. Further examination shows that the sensing performance of the AuNS-modified SPCE produced an increase in electrochemical surface area (ECSA) at 17.25 times higher than the bare electrode, a sensitivity of 0.056 µA mM−1 cm−2 with a wide linear range of 0.2–50 µM and a detection limit of 0.33 µM. In addition, AuNS-modified SPCE can selectively detect dopamine among other interfering analytes such as ascorbic acid, urea, and uric acid, which commonly coexist in the body fluid. This work demonstrated that AuNS-modified SPCE is a prospective sensing platform for non-enzymatic dopamine detection.
