Nature Communications (May 2022)

Codon-specific Ramachandran plots show amino acid backbone conformation depends on identity of the translated codon

  • Aviv A. Rosenberg,
  • Ailie Marx,
  • Alex M. Bronstein

DOI
https://doi.org/10.1038/s41467-022-30390-9
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Genetic code redundancies are considered inconsequential to protein structure. This study uncovers a dependence between local amino acid conformation in folded proteins and the identity of the codon from which that amino acid was translated.