Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways

Yuhree Kim; Jie Yin; Hailiang Huang; Eric Jorgenson; Hélène Choquet; Maryam M. Asgari

doi:10.1038/s42003-022-03301-3

Communications Biology (Apr 2022)

Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways

Yuhree Kim,
Jie Yin,
Hailiang Huang,
Eric Jorgenson,
Hélène Choquet,
Maryam M. Asgari

Affiliations

Yuhree Kim: Department of Dermatology, Massachusetts General Hospital
Jie Yin: Division of Research, Kaiser Permanente Northern California
Hailiang Huang: Analytic and Translational Genetics Unit, Massachusetts General Hospital
Eric Jorgenson: Regeneron Genetics Center
Hélène Choquet: Division of Research, Kaiser Permanente Northern California
Maryam M. Asgari: Department of Dermatology, Massachusetts General Hospital

DOI: https://doi.org/10.1038/s42003-022-03301-3
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 9

Abstract

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A study on actinic keratosis identifies multiple loci showing genome-wide significant association with implicated genes within biological pathways for pigmentation, immune regulation, and extracellular matrix homeostasis.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal