The Korean Journal of Gastroenterology (Oct 2016)

Gastric Mucosa-associated Lymphoid Tissue Lymphoma Based on Outcome of Domestic Treatment

  • Jin Tae Jung

DOI
https://doi.org/10.4166/kjg.2016.68.4.175
Journal volume & issue
Vol. 68, no. 4
pp. 175 – 178

Abstract

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Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with Helicobacter pylori infection. H. pylori eradication can be performed as a primary therapy regardless of H. pylori status. In Korea, six articles were published about low-grade gastric MALT lymphoma with H. pylori. Complete regression rate after H. pylori eradication is reported at 74.5% to 94.4%. Radiotherapy results in favorable clinical long-term outcomes in patients with early-stage gastric MALT lymphoma who fail H. pylori eradication therapy and those who are H. pylori negative. Chemotherapy could be reserved for patients with metastatic or high-grade lymphoma. In gastric MALT lymphoma, patients with polypoid type on initial endoscopy had a higher likelihood of recurrence than those with diffuse infiltration or ulceration types. The depth of invasion, location of lesions, and chromosomal abnormality with t(11;18) together are predictive factors for failure to remission by H. pylori eradication. (Korean J Gastroenterol 2016;68:175-178)

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