SYNTHESIS AND CHARACTERIZATION OF POLY(LACTIC-CO-GLYCOLIC-ACID) MICROPARTICLES LOADED WITH FOOT-AND-MOUTH DISEASE VIRUS 40–60 SYNTHETIC PEPTIDE

Abstract

The aim of the research was to synthesize and characterize the poly (lactic-co-glycolic-acid) microparticles loaded with foot-and-mouth disease virus 40-60 synthetic peptide. Single emulsion solvent evaporation method was used for the production of microparticles with theree diferent (5; 10 and 15 mg) peptide amounts and obtained microparticles were characterized by using yield reaction, encapsulation efficiency, drug loading, particle size, polydispersity index, and zeta potential.

Keywords

• virus of the foot-and-mouth disease
• poly (lactic-co-glycolic-acid) microparticles