On the Mechanical Properties of Microfibre-Based 3D Chitinous Scaffolds from Selected Verongiida Sponges
Tomas Duminis,
Marcin Heljak,
Wojciech Święszkowski,
Alexander Ereskovsky,
Izabela Dziedzic,
Marek Nowicki,
Martyna Pajewska-Szmyt,
Alona Voronkina,
Stefan R. Bornstein,
Hermann Ehrlich
Affiliations
Tomas Duminis
Centre for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznan, Poland
Marcin Heljak
Faculty of Materials Science and Engineering, Warsaw University of Technology, ul. Wołoska 141, 02-507 Warsaw, Poland
Wojciech Święszkowski
Faculty of Materials Science and Engineering, Warsaw University of Technology, ul. Wołoska 141, 02-507 Warsaw, Poland
Alexander Ereskovsky
Institut Méditerranéen de Biodiversité et d’Écologie Marine et Continentale (IMBE), Aix Marseille Université, Station Marine d’Endoume, Rue de la Batterie des Lions, 13007 Marseille, France
Izabela Dziedzic
Centre for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznan, Poland
Marek Nowicki
Centre for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznan, Poland
Martyna Pajewska-Szmyt
Centre for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznan, Poland
Alona Voronkina
Department of Pharmacy, National Pirogov Memorial Medical University, Vinnytsya, Pirogov Str. 56, 21018 Vinnytsia, Ukraine
Stefan R. Bornstein
Department of Medicine III, Universitz Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetschelstrasse 74, 01307 Dresden, Germany
Hermann Ehrlich
Centre for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznan, Poland
Skeletal constructs of diverse marine sponges remain to be a sustainable source of biocompatible porous biopolymer-based 3D scaffolds for tissue engineering and technology, especially structures isolated from cultivated demosponges, which belong to the Verongiida order, due to the renewability of their chitinous, fibre-containing architecture focused attention. These chitinous scaffolds have already shown excellent and promising results in biomimetics and tissue engineering with respect to their broad diversity of cells. However, the mechanical features of these constructs have been poorly studied before. For the first time, the elastic moduli characterising the chitinous samples have been determined. Moreover, nanoindentation of the selected bromotyrosine-containing as well as pigment-free chitinous scaffolds isolated from selected verongiids was used in the study for comparative purposes. It was shown that the removal of bromotyrosines from chitin scaffolds results in a reduced elastic modulus; however, their hardness was relatively unaffected.
