PLoS Medicine (Apr 2014)

A physicians' wish list for the clinical application of intestinal metagenomics.

  • Ingeborg Klymiuk,
  • Christoph Högenauer,
  • Bettina Halwachs,
  • Gerhard G Thallinger,
  • W Florian Fricke,
  • Christoph Steininger

DOI
https://doi.org/10.1371/journal.pmed.1001627
Journal volume & issue
Vol. 11, no. 4
p. e1001627

Abstract

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Christoph Steininger and colleagues explore how multiple infectious, autoimmune, metabolic, and neoplastic diseases have been associated with changes in the intestinal microbiome, although a cause-effect relationship is often difficult to establish. Integration of metagenomics into clinical medicine is a challenge, and the authors highlight clinical approaches that are of high priority for the useful medical application of metagenomics. Please see later in the article for the Editors' Summary.