Research progress of circular RNAs in prostate cancer

Abstract

Circular RNAs (circRNAs) are non-coding RNAs with unique covalently closed circular structures and are widely found in eukaryotic cells. Recent studies have shown that circRNAs are involved in the patho-physiological processes of various diseases including malignant tumors through regulating microRNAs, binding to proteins and regulating transcription and splicing process. The special structure and complex functions of circRNAs make them have great research potential in the field of cancer. Prostate cancer(PCa) is one of the most common malignancies among the world. The the pathogenesis and treatment of PCa still need to be further studied.

Keywords

• circular rnas|prostate cancer|gene regulation