Palliative Medicine Reports (Nov 2022)

Palliative Radiation Therapy without Chemotherapy for a Patient with Monomorphic Epitheliotropic Intestinal T Cell Lymphoma: A Case Report

  • Takeaki Kusada,
  • Takuro Ariga,
  • Kaori Kina,
  • Yohei Okubo,
  • Masaya Kiyuna,
  • Tsutomu Kadekaru,
  • Takeshi Tomiyama,
  • Hisashi Kamiya,
  • Masaki Gibo,
  • Akihiro Nishie

DOI
https://doi.org/10.1089/PMR.2022.0011
Journal volume & issue
Vol. 3, no. 1
pp. 272 – 278

Abstract

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Monomorphic epitheliotropic intestinal T cell lymphoma (MEITL), which used to be known as type 2 enteropathy-associated T cell lymphoma, is a rare lymphoma and is generally treated with chemotherapy. However, the MEITL prognosis is poor, and intestinal lymphoma including MEITL has the risk of bowel perforation not only at presentation but also during chemotherapy. A 67-year-old man was diagnosed with MEITL after presenting in our emergency room with bowel perforation. He and his family did not opt for the administration of anticancer drugs because of the risk of bowel perforation. However, they wanted the patient to receive palliative radiation therapy without chemotherapy. This treatment shrunk the tumor size without causing severe complications or decline in the quality of life, until he accidentally died due to traumatic intracranial hematoma. Considering the potential efficacy and safety of this treatment, it should be studied in more patients with MEITL.

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