A Rare Malignancy Postrenal Transplantation – The Dark Side of Success

Abstract

Solid organ transplant patients are at an increased risk of developing various types of malignancies. Herein, we have reported the case of a 32-year-old male patient, who presented with a nodular mass in the left shoulder 4 months after undergoing deceased donor renal transplantation. Local excision and biopsy were performed which revealed a malignant spindle cell tumor. Immunohistochemistry revealed S100 faint nuclear positivity in a few cells, CD34 positive, Ki67 1% low, and SMA negative suggestive of low-grade fibroblastic origin spindle cell tumor. This is a rare low-grade sarcoma with a high rate of local recurrence, rarely leading to amputation. Metastasis to the lungs and liver has been seldom reported. Our patient had local recurrence twice posttransplant for which he underwent wide local excision.

Keywords

• fibrosarcoma
• renal transplantation
• spindle cell tumor