Application of Programmable Tetrahedral Framework Nucleic Acid-Based Nanomaterials in Neurological Disorders: Progress and Prospects

Xingyu Chen; Yu Xie; Zhiqiang Liu; Yunfeng Lin; Yunfeng Lin

doi:10.3389/fbioe.2021.782237

Frontiers in Bioengineering and Biotechnology (Nov 2021)

Application of Programmable Tetrahedral Framework Nucleic Acid-Based Nanomaterials in Neurological Disorders: Progress and Prospects

Xingyu Chen,
Yu Xie,
Zhiqiang Liu,
Yunfeng Lin,
Yunfeng Lin

Affiliations

Xingyu Chen: State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
Yu Xie: State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
Zhiqiang Liu: State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
Yunfeng Lin: State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
Yunfeng Lin: College of Biomedical Engineering, Sichuan University, Chengdu, China

DOI: https://doi.org/10.3389/fbioe.2021.782237
Journal volume & issue: Vol. 9

Abstract

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Tetrahedral framework nucleic acid (tFNA), a special DNA nanodevice, is widely applied in diverse biomedical fields. Due to its high programmability, biocompatibility, tissue permeability as well as its capacity for cell proliferation and differentiation, tFNA presents a powerful tool that could overcome potential barriers in the treatment of neurological disorders. This review evaluates recent studies on the use and progress of tFNA-based nanomaterials in neurological disorders.

Published in Frontiers in Bioengineering and Biotechnology

ISSN: 2296-4185 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Technology: Chemical technology: Biotechnology
Website: http://www.frontiersin.org/bioengineering_and_biotechnology

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Abstract

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