Electrospun VDF-TeFE Scaffolds Modified by Copper and Titanium in Magnetron Plasma and Their Antibacterial Activity against MRSA
Arsalan D. Badaraev,
Marat I. Lerner,
Dmitrii V. Sidelev,
Evgeny N. Bolbasov,
Sergei I. Tverdokhlebov
Affiliations
Arsalan D. Badaraev
School of Nuclear Science & Engineering, Tomsk Polytechnic University, 30, Lenin Avenue, 634050 Tomsk, Russia
Marat I. Lerner
Institute of Strength Physics and Materials Sciences of Siberian Branch of the Russian Academy of Sciences, 2/4, Akademicheskii Avenue, 634055 Tomsk, Russia
Dmitrii V. Sidelev
School of Nuclear Science & Engineering, Tomsk Polytechnic University, 30, Lenin Avenue, 634050 Tomsk, Russia
Evgeny N. Bolbasov
School of Nuclear Science & Engineering, Tomsk Polytechnic University, 30, Lenin Avenue, 634050 Tomsk, Russia
Sergei I. Tverdokhlebov
School of Nuclear Science & Engineering, Tomsk Polytechnic University, 30, Lenin Avenue, 634050 Tomsk, Russia
Copolymer solution of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) was used for electrospinning of fluoropolymer scaffolds. Magnetron co-sputtering of titanium and copper targets in the argon atmosphere was used for VDF-TeFE scaffolds modification. Scanning electron microscopy (SEM) showed that scaffolds have a nonwoven structure with mean fiber diameter 0.77 ± 0.40 μm, mean porosity 58 ± 7%. The wetting angle of the original (unmodified) hydrophobic fluoropolymer scaffold after modification by titanium begins to possess hydrophilic properties. VDF-TeFE scaffold modification by titanium/copper leads to the appearance of strong antibacterial properties. The obtained fluoropolymer samples can be successfully used in tissue engineering.
