Estrogen Receptor beta (ERβ) Regulation of Lipid Homeostasis—Does Sex Matter?

Christina Savva; Marion Korach-André

doi:10.3390/metabo10030116

Metabolites (Mar 2020)

Estrogen Receptor beta (ERβ) Regulation of Lipid Homeostasis—Does Sex Matter?

Christina Savva,
Marion Korach-André

Affiliations

Christina Savva: Department of Medicine, Metabolism Unit and KI/AZ Integrated Cardio Metabolic Center (ICMC), Metabolism and Karolinska Institutet at Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden
Marion Korach-André: Department of Medicine, Metabolism Unit and KI/AZ Integrated Cardio Metabolic Center (ICMC), Metabolism and Karolinska Institutet at Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden

DOI: https://doi.org/10.3390/metabo10030116
Journal volume & issue: Vol. 10, no. 3
p. 116

Abstract

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In this communication, we aim to summarize the role of estrogen receptor beta (ERβ) in lipid metabolism in the main metabolic organs with a special focus on sex differences. The action of ERβ is tissue-specific and acts in a sex-dependent manner, emphasizing the necessity of developing sex- and tissue-selective targeting drugs in the future.

Published in Metabolites

ISSN: 2218-1989 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.mdpi.com/journal/metabolites

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