Communications Biology (Jan 2023)

Transcriptomic survey of key reproductive and metabolic tissues in mouse models of polycystic ovary syndrome

  • Yu Pei,
  • Sanjiv Risal,
  • Hong Jiang,
  • Haojiang Lu,
  • Eva Lindgren,
  • Elisabet Stener-Victorin,
  • Qiaolin Deng

DOI
https://doi.org/10.1038/s42003-022-04362-0
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 15

Abstract

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Transcriptomic mapping of key reproductive and metabolic tissues and oocytes in mouse models of polycystic ovary syndrome reveals that the hypothalamus is susceptible to fetal programming while adipose and ovary are more affected upon postnatal androgen exposure.